Image of mouth probiotics, ToothGuard - a dental probiotic for healthy teeth and gums. | Blis Probiotics

ToothGuard with BLIS M18 | Advanced Dental Health

ToothGuard represents a new generation of advanced oral probiotics scientifically developed to support healthy teeth and gums. It works by crowding out the bad bacteria - leaving them nowhere to hide, and colonising the mouth with good, healthy bacteria.

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An advanced Dental Health probiotic that targets hard to reach bacteria to support healthy teeth & gums.​

Founded in NZ
Pregnancy Safe
Fridge Free

ToothGuard with BLIS M18™

Customer Reviews

Based on 57 reviews
Willow’s World

Love this product. Essential to my night time oral care regime.

Angela Lithgow

ToothGuard with BLIS M18™ | Advanced Dental Health

Relief from sore gums!

I have sensitive gums and lately they've been really sore overnight especially so I bought some Blis probiotics and am using them regularly and lo & behold the symptoms have disappeared! I'm so happy and recommend this to anyone seeking relief from itchy or substandard gums . . . something is happening to make them better . . . .


Excellent product. Works well.

My dental health must have!

I have periodontal disease and use M18 to complement my Dental Hygienist and Periodontic treatments. M18 has helped keep my gums much healthier than before I started taking it, even with aggressive dental treatment. I highly recommend this product.

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Why choose blis?

Here at BLIS we've decided to get back to basics, think of this like a BLIS 101 class, focusing on our core and pioneering products - oral probiotics, or probiotics for the mouth and throat.

Keep reading if you'd like to learn more about what oral probiotics are, how they work, and most importantly how you can benefit from them.

An image of a researcher experimenting with probiotics in a lab

Backed by science

BLIS Probiotics champions healthy mouths for all through their innovative, scientifically developed and researched probiotics for the mouth and throat.

BLIS Probiotics are leaders when it comes to applying the science of​ probiotics to the mouth and throat by adding the good bacteria in to crowd out and target the harmful bacteria.

Frequently Asked Questions

Glad you asked! BLIS is an acronym for Bacteriocin-Like Inhibitory Substances - and the core of our science and advanced probiotics.

Probiotics are good bacteria that have been characterised for their beneficial properties. They work by rapidly reproducing and crowding out any bad bacteria. You might be familiar with probiotics aimed to maintain a good balance in the gut, but your gut is not the only place that has a microbiome worth keeping in balance.

Advanced probiotics are slightly different in that they also provide the benefit of producing bacteriocins (small proteins) that are inhibitory against other bacteria species. So, not only do they crowd out the bad bacteria, they inhibit them with bacteriocins.

However, not all probiotic strains can do this. BLIS K12™ and BLIS M18™ are both advanced probiotics strains that utilise Streptococcus salivarius, which means that they have this additional capability.

Streptococcus salivarius is a species of spherical, gram-positive, facultative anaerobic bacteria that is both catalase and oxidase negative. S. salivarius colonises (usually in chains) the mouth and upper respiratory tract of humans just a few hours after birth, making further exposure to the bacteria harmless in most circumstances.

Some strains of S. salivarius are marketed as a probiotic for oral health. Some strains of S. salivarius are found to produce BLIS (the above-mentioned bacteriocin-like inhibitory substances) which are peptides that display interspecies inhibition.

BLIS K12™ and BLIS M18™ are both specific strains of Streptococcus salivarius and the core of our oral probiotics.

As noted, most probiotics are targeted towards the gut and digestive tract.

Oral probiotics, however, are those that support the mouth and throat, protecting the oral cavity (a fancy way of saying mouth, teeth, gums and throat).

BLIS K12™ probiotics populate the mouth and throat with good bacteria, crowding out the bad. In science terms – this is known as ‘bacterial interference’.

By creating a forcefield, oral probiotics can support mouth and throat health. BLIS K12™ is also used in our FreshBreath kits which restore the balance of good bacteria to the oral cavity and can aid bad breath and halitosis.

BLIS M18™ works in a similar way but it is targeted specifically at the bad bacteria that can cause teeth and gum issues.